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Did you mean stephen m mclaughlin[Author] (1 results)?
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Gong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B. Gong GQ, et al. Among authors: mclaughlin sh. Nature. 2023 Jun;618(7963):159-168. doi: 10.1038/s41586-023-05972-2. Epub 2023 May 24. Nature. 2023. PMID: 37225977 Free PMC article.
Disease-specific tau filaments assemble via polymorphic intermediates.
Lövestam S, Li D, Wagstaff JL, Kotecha A, Kimanius D, McLaughlin SH, Murzin AG, Freund SMV, Goedert M, Scheres SHW. Lövestam S, et al. Among authors: mclaughlin sh. Nature. 2024 Jan;625(7993):119-125. doi: 10.1038/s41586-023-06788-w. Epub 2023 Nov 29. Nature. 2024. PMID: 38030728 Free PMC article.
Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Yatskevich S, Muir KW, Bellini D, Zhang Z, Yang J, Tischer T, Predin M, Dendooven T, McLaughlin SH, Barford D. Yatskevich S, et al. Among authors: mclaughlin sh. Science. 2022 May 20;376(6595):844-852. doi: 10.1126/science.abn3810. Epub 2022 Apr 14. Science. 2022. PMID: 35420891 Free PMC article.
Activation of GCN2 by the ribosomal P-stalk.
Inglis AJ, Masson GR, Shao S, Perisic O, McLaughlin SH, Hegde RS, Williams RL. Inglis AJ, et al. Among authors: mclaughlin sh. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4946-4954. doi: 10.1073/pnas.1813352116. Epub 2019 Feb 25. Proc Natl Acad Sci U S A. 2019. PMID: 30804176 Free PMC article.
Target-induced clustering activates Trim-Away of pathogens and proteins.
Zeng J, Santos AF, Mukadam AS, Osswald M, Jacques DA, Dickson CF, McLaughlin SH, Johnson CM, Kiss L, Luptak J, Renner N, Vaysburd M, McEwan WA, Morais-de-Sá E, Clift D, James LC. Zeng J, et al. Among authors: mclaughlin sh. Nat Struct Mol Biol. 2021 Mar;28(3):278-289. doi: 10.1038/s41594-021-00560-2. Epub 2021 Feb 25. Nat Struct Mol Biol. 2021. PMID: 33633400 Free PMC article.
Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Fischer ES, Yu CWH, Bellini D, McLaughlin SH, Orr CM, Wagner A, Freund SMV, Barford D. Fischer ES, et al. Among authors: mclaughlin sh. EMBO Rep. 2021 Jul 5;22(7):e52242. doi: 10.15252/embr.202052242. Epub 2021 May 19. EMBO Rep. 2021. PMID: 34013668 Free PMC article.
CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Ochi T, Quarantotti V, Lin H, Jullien J, Rosa E Silva I, Boselli F, Barnabas DD, Johnson CM, McLaughlin SH, Freund SMV, Blackford AN, Kimata Y, Goldstein RE, Jackson SP, Blundell TL, Dutcher SK, Gergely F, van Breugel M. Ochi T, et al. Among authors: mclaughlin sh. Structure. 2020 Jun 2;28(6):674-689.e11. doi: 10.1016/j.str.2020.04.010. Epub 2020 May 5. Structure. 2020. PMID: 32375023 Free PMC article.
57 results